Mitochondria-Targeted Antioxidants for Treatment of Hearing Loss: A Systematic Review
Mitochondrial dysfunction is associated with the etiologies of sensorineural hearing loss, such as age-related hearing loss, noise- and ototoxic drug-induced hearing loss, as well as hearing loss due to mitochondrial gene mutation.Mitochondria are the main sources of reactive oxygen species (ROS) and ROS-induced oxidative stress is involved in coch